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Development and evaluation of tissue optical phantoms

The development and validation of optical imaging methods require measurements on artificial imaging targets, known as phantoms. Tissue phantoms are needed for testing theoretical predictions; calibrating instruments, and verifying techniques for various methods of optical bio-medical diagnostics, including spatially resolved diffuse reflectance measurements, time-, frequency-, and spatial-domain diffuse tissue spectroscopy and tomography, hyperspectral imaging, fluorescence spectroscopy and imaging, as well as photoacoustic imaging.