Atomic Physics

Faculty of Engineering, LTH

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Tissue viability monitoring using non-invasive imaging techniques

In certain cases of skin cancer excision, removal skin transplants are used. Periorbital tumour reconstruction is very crucial and monitoring of the flap tissue blood flow, composition and function can improve the outcome of the procedure.

Studies are performed in experimental pigs and in patients going through reconstructive surgery following periorbital tumour excision. If we know how the blood flow and the survival of tissue are affected by these surgical procedures, it will be easier to perform simpler and less invasive reconstructions following tumour removal. We will study and develop the use of non-invasive imaging techniques including Laser Speckle Contrast Imaging (LSCI), Diffuse Reflectance Spectroscopy (DRS) and Photoacoustic Imaging (PAI) in experimental pigs and in patients going through reconstructive surgery. Through these developments, we believe that it will be possible to optimize surgical techniques, improve the result of surgery and reduce the suffering of the patient.

Laser Speckle Contrast Imaging (LSCI). Photo: Sheikh 2015.
Pulse Oximetry (PO) and Diffuse Reflectance Spectroscopy (DRS). Photo: Reistad 2017.
Photoacoustics Imaging (PAI). Photo: Reistad 2017.