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Atomic Physics

Faculty of Engineering, LTH

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Biophotonics

The development and application of optical diagnostic tools and therapies

We  the study of the interaction of light and tissue and seek deeper understanding of basic optical interactions in tissues as well as develope new optical and imaging techniques and deploy it in imaging and diagnostic applications. This research and developement is conducted at the interfaces of the disciplines of optics, biomedical engineering, biology and clinical medicine and is conducted in close collaborations with researchers and clinicians in medicine and biology. Our activities include: in vivo monitoring of human tissue, as well as industrial applications such as food quality control and spectroscopy of pharmaceutical materials. 

Research at the Division of Atomic Physics, Lund University

The biophotonics research at the Division of Atomic Physics (Lund University) includes:

  • Optical guidance in periorbital tumor surgery
  • Tissue viability monitoring using non-invasive imaging techniques
  • Real time assessment of liver function
  • Developing photoacoustic imaging into a novel diagnostic tool for skin cancer
  • Non‐surgical diagnostic techniques for Giant Cell Arteritis
  • Non-invasive monitoring of gas in the lungs and intestines of newborn infants
  • Monitoring of tissue oxygen saturation
  • Development and evaluations of tissue optical phantoms

Collaboration with South China Normal University, Guangzhou

The Lund University biophotonics research is closely connected to the Center for Optical and Electromagnetic Research at South China Normal University (SCNU) in Guangzhou. Since 6 years, two senior members of the Lund group have part-time appointments at SCNU, where they in close connection to Lund University pursue research in the biophotonics area with several sub-directions, including:

  • Diagnostics of middle-ear and sinus cavities (aiming at fighting the development of microbial resistance to anti-biotics).
  • Diagnostics of femoral head degeneration (aiming at detecting the development of gas-filled cavities in decaying bone).
  • Quality control of food stuffs (fresh fruit, hen eggs (including fertilized eggs), and packed food)
  • Monitoring of flying  insects (pollinators, disease vectors, and agricultural pests)

Experimental techniques used in the studies include Gas in Scattering Media Absorption Spectroscopy (GASMAS), reflectance and fluorescence spectroscopy, sometimes combined with light detection and ranging (lidar) techniques.

Optical guidance in periorbital tumor surgery

Clinical Photoacoustics Imaging

Real time assessment of liver function

Monitoring of tissue oxygen saturation

Development and evaluations of tissue optical phantoms

Diagnostics of middle-ear and sinus cavities

Diagnostics of femoral head degeneration

Quality control of food stuffs

Monitoring of flying insects